Graded challenge:
Administration of 1/100 of the therapeutic dose; if no reaction, then 30-60 minutes later give 1/10 of the therapeutic dose, and if no reaction, then 30-60 minutes later, give full therapeutic dose.
Administration of 1/100 of the therapeutic dose; if no reaction, then 30-60 minutes later give 1/10 of the therapeutic dose, and if no reaction, then 30-60 minutes later, give full therapeutic dose.