Children > 3 months
- Consider need for acyclovir if HSV encephalitis possible.
Usual Pathogens
S. pneumoniae
N. meningitidis
H. influenzae
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Ceftriaxone | 100mg/kg/d IV div q12h | S. pneumoniae - 10 days N. meningitidis - 5-7 days H. influenzae - 7-10 days |
| + | ||
| Vancomycin | 60mg/kg/d IV div q6h |
Alternative only if severe/anaphylactic ß-lactam allergy
| Empiric Therapy | Duration | |
|---|---|---|
| Meropenem | 120mg/kg/d IV div q8h | S. pneumoniae - 10 days N. meningitidis - 5-7 days H. influenzae - 7-10 days |
| + | ||
| 60mg/kg/d IV div q6h |