Nonchlamydial / nongonococcal

- Evaluate history for use of spermicides, deodorants, chemical douches.

Usual Pathogens
Potential etiology

Mycoplasmoides genitalium (previously Mycoplasma genitalium)
Trichomonas vaginalis
Bacterial vaginosis
Herpes simplex


Empiric Therapy Dose Duration
Azithromycin 1g PO 1 dose

If unresponsive to azithromycin:

Empiric Therapy Dose Duration
Doxycycline 100mg PO bid 7 days


If persistent symptoms after treatment with azithromycin and doxycycline, collect additional specimens for M. genitalium, T. vaginalis, herpes simplex virus and bacterial vaginosis, and then target treatment based on results.