Neonates
- Recommend blood culture.
- If meningitis is possible (e.g. fever, lethargy, or poor feeding), do a lumbar puncture and use meningitic doses of cloxacillin + [gentamicin or cefotaxime].
Usual Pathogens
S. aureus
Group B Streptococci
Enterobacterales
Group A Streptococci
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Cefazolin | 75mg/kg/d IV div q8h | 10-14 days |
| + | ||
| Gentamicin | 4-5mg/kg IV q24h |