Impetigo

Superficial nonfollicular pustules

- No evidence that disinfecting solutions are of any value.

 
Usual Pathogens
Bullous:

S. aureus

 
Nonbullous, honey crust lesions:

Group A Streptococci

Limited involvement/disease

Empiric Therapy Dose Duration
Mupirocin 2% tid topically until resolved (max 7 days)
or    
Fusidic acid 2% tid-qid topically until resolved (max 7 days)

Unresponsive to topical or indication for systemic antibiotic

Empiric Therapy Dose Duration
Cloxacillin 500mg PO qid until resolved (max 7 days)
or    
Cephalexin 500mg PO qid until resolved (max 7 days)

Penicillin and cephalexin allergy

Empiric Therapy Dose Duration
Erythromycin 500mg PO qid until resolved (max 7 days)
or    
Clindamycin 300mg PO qid until resolved (max 7 days)