Neonates
- Bone cultures recommended as occasionally other organisms may be involved.
- If meningitis is possible (e.g. fever, lethargy, or poor feeding), recommend lumbar puncture.
Usual Pathogens
S. aureus
Group A, B Strep
Enterobacterales
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Cefotaxime | 200mg/kg/d IV div q6h | 4-6 weeks |
Neonate/mother colonized with MRSA
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Vancomycin | 45mg/kg/d IV div q8h | 4-6 weeks |
| + | ||
| Cefotaxime | 200mg/kg/d IV div q6h |