2° to paranasal sinusitis
- Consider otolaryngology consult.
- Stepdown to oral agents when clinically improved.
Usual Pathogens
S. aureus/MRSA
Group A Streptococci
S. pneumoniae
H. influenzae
Mild/Afebrile
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Amoxicillin-clavulanate | Paediatric: 40mg/kg/d PO div tid | 7-10 days |
| Adult: 875mg PO bid | 7-10 days |
If MRSA suspected
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Add TMP/SMX | Paediatric: 8-12mg TMP/kg/d PO div bid | 7-10 days |
| Adult: 1-2 DS tabs PO bid | 7-10 days |
Moderate/Severe
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Cefuroxime | Paediatric: 100-150mg/kg/d IV div q8h | 7-10 days |
| Adult: 750mg IV q8h | 7-10 days | |
| or | ||
| Ceftriaxone | Paediatric: 50-75mg/kg IV q24h | 7-10 days |
| Adult: 1-2g IV daily | 7-10 days |
If MRSA suspected
| Empiric Therapy | Dose | Duration |
|---|---|---|
| Add Vancomycin | Paediatric: 60mg/kg/d IV div q6h | 7-10 days |
| Adult: 15mg/kg IV q8-12h | 7-10 days |