2° to skin trauma

- Types of trauma include:

  • puncture wounds
  • lacerations
  • insect bites
  • animal bites.
Usual Pathogens

S. aureus/MRSA
Group A Streptococci
Anaerobes

Mild-moderate

Empiric Therapy Dose Duration
Amoxicillin-clavulanate Paediatric: 40mg/kg/d PO div tid 7-10 days
  Adult: 875mg PO bid 7-10 days
+    
TMP/SMX Paediatric: 8-12mg TMP/kg/d PO div bid 7-10 days
  Adult: 1-2 DS tabs PO bid 7-10 days

Severe

Empiric Therapy Dose Duration
Vancomycin Paediatric: 60mg/kg/d IV div q6h 7-10 days
  Adult: 15mg/kg IV q8-12h 7-10 days
+    
Ceftriaxone Paediatric: 50-75mg/kg IV q24h 7-10 days
  Adult: 1-2g IV daily 7-10 days
+    
Metronidazole Paediatric: 30mg/kg/d IV/PO div q12h 7-10 days
  Adult: 500mg IV/PO q12h 7-10 days