2° to trauma

- Tailor antibiotic therapy to C&S results.

 
Usual Pathogens

S. aureus
Group A Streptococci
Bacillus spp
Anaerobes

Paediatric

Empiric Therapy Dose Duration
Vancomycin 60mg/kg/d IV div q6h 10-14 days
+    
Ceftriaxone 100mg/kg/d IV div q12h  
+    
Metronidazole PO/IV 30mg/kg/d PO/IV div q8h  

Adult

Empiric Therapy Dose Duration
Vancomycin 15mg/kg IV q8-12h 10-14 days
+    
Ceftriaxone 2g IV q12h  
+    
Metronidazole PO/IV 500mg PO/IV q8h